RESEARCH PROJECTS

CHALLENGES IN MANAGEMENT OF STEMI CARE DURING COVID-19 PANDEMIC

Aniruddha Singh, MD, FACC - We compared performance measures and outcomes of all patients who presented to our facility during COVID pandemic with STEMI. This study period was compared to a matched cohort during the same time period last year.

EKG CHARACTERISTICS IN PRESENTING WITH COVID-19

Aniruddha Singh, MD, FACC - We are evaluating consecutive EKGs and patient’s presenting with COVID-19 at our facility.  Our aim is to find EKG characteristics which would help identify sicker COVID-19 patients.

OUT-PATIENT TELEHEALTH PERFORMANCE IN A CARDIOLOGY CLINIC

Aniruddha Singh, MD, FACC - We’re performing an outpatient telemetry medicine survey through our cardiology clinic to evaluate patient’s satisfaction, compliance and clinical outcomes during the COVID 19.

PERIODONTAL STUDY- ACUTE CORONARY SYNDROME TRIAL (PD-ACS TRIAL)

Kris Pfirman, DO, Tim Donley, DDS, Mohammed Kazimuddin, MD, FACC, FSCAI- This is a randomized control trial to evaluate for a possible reduction in myocardial infarction and stroke in patients with periodontal inflammation who undergo treatment to relieve oral inflammation. There is anecdotal data to suggest that treating dental inflammation might reduce myocardial infarction however there is no randomized data. Our study will be the first randomized prospective study to evaluate this concept.

FITBIT TRACKING ACTIVITY LEVEL AS A PREDICTOR FOR HEART FAILURE EXACERBATION (FITTAP HF) STUDY

Jacqueline Dawson Dowe, MD, FACC - The hypothesis of the study is that worsening heart failure symptoms lead to decreased activity levels, which can be detected using FitBits to track their steps and heart rates.  By knowing their reduced activity levels we can intervene early and prevent readmission with heart failure.  As a randomized, prospective trial FITTAP HF will be the first study to evaluate this non invasive modality in reducing HF rehospitalization.

WOMENS' ISCHEMIA TRIAL TO REDUCE EVENTS IN NON-OBSTRUCTIVE CAD (WARRIOR)- SITE CO-PI

Jacqueline Dawson Dowe, MD, FACC, Aniruddha Singh, MD, FACC - WARRIOR is a multicenter, prospective, randomized, blinded outcome evaluation evaluating Intensive Medical Therapy vs Usual care in symptomatic women with ischemia but no obstructive CAD. The primary outcomes are first occurrence of death, MI, stroke/TIA.  Hospitalization for chest pain or heart failure.  Secondary outcomes include quality of life, health resource consumption, angina, CV death and primary outcome components.  The hypothesis is that intensive medical therapy would reduce adverse cardiovascular events by 20% compared to usual care. This will be the first study in the US to provide treatment insights on women who present with chest pain concerning for CAD but do not have significant coronary stenosis anatomically.

MULTI-VARIABLE ANALYSIS OF ECHOCARDIOGRAPHIC PARAMETERS IN PATIENTS PRIOR TO AND AFTER GASTRIC SLEEVE SURGERY

Sajjad Haider, Atif Tatari, Caitlyn Galloway, Muhammad Amjad, Aniruddha Singh, MD, FACC, Jacqueline Dawson Dowe, MD, FACC. Journal of the American College of Cardiology. Volume 75, issue 11 Supplement 1, March 2020

IMPACT OF FLUOROSCOPY DOZE UTILITZED DURING CORONARY ANGIOGRAPHY ON MAJOR ADVERSE CARDIAC EVENTS

Sajjad haider, Akah Doshi, Atif tatari, Douglas McElroy, Aniruddha Singh. 15th Annual Complex Cardiovascular Catheter Therapeutics (C3): Advanced Endovascular and Coronary Intervention Global Summit. Journal of Invasive Cardiology. Vol 31-Issue 11-Nov 2019

RETROSPECTIVE OUTCOMES ANALYSIS AFTER LEFT MAIN CORONARY ARTERY PERCUTANEOUS CORONARY REVASCULARIZATION

JasonCohen DO, Atif Tatari DO, Doug McElroy PhD, Charles Morrow DO, Mohammad Abdul-Waheed MD, FACC, FSCAI, Muhammad S. Akbar MD, FACC, FSCIA, Jacqueline Dawson Dowe MD, FACC, Madhav Lavu MD, Aniruddha Singh MD, FACC, Mohammad Kazimuddin MD, FACC, FSCAI. Presented at KY ACC 2017.